Atorvastatin
Atorvastatin questions and answers
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Q: what are the side effects of taking ATORVASTATIN for reducing cholesterol?
am taking lipitor which contains atorvastatin mside effects of the medicament and are there articles which talk about this?
A: According to the prescribing information for Lipitor -
Atorvastatin is generally well-tolerated, and side effects are rare. Minor side effects include constipation, diarrhea, fatigue, gas, heartburn, and headache. Atorvastatin should be used with caution in patients with alcohol or other liver diseases. Persistently abnormal liver tests during treatment are rare but may require discontinuation of the medication. Rare cases of muscle inflammation (myositis) and breakdown have been reported with other drugs in this class (HMGCoA reductase antagonists), and it is assumed that this side effect also may occur with atorvastatin. Muscle breakdown causes the release of muscle protein (myoglobin) into the blood and accumulation of the protein in the kidney tubules, resulting in kidney failure.
The medical community's idea of side effects seems to be different than your and my idea of side effects. They talking about people dying, and how rare it is. On the other hand, if you ask your friends, neighbors, family members, and co-workers about statins, most will tell you that they generally started to feel crappy once they started taking statins. I'm talking about fatigue, and a general feeling of ill health.
Yes, there are many many many articles about statins - and the writers generally talk about the severe side effects that kill you. Nobody seems to be talking about the fact that the statins tend to ruin quality of life.
Q: I've been prescribed Atorvastatin and am worried about side effects?
I was previously prescribed Simvastatin, but due to nasty side effects (weakness, fatigue, muscle pain) I cam off them, and declined my doctors advice to take another statin.I have had blood tests recently and my cholesterol level has gone back up to 7.4 so he has told me I sholud take another statin, and has prescribed Atorvastatin. Can anyone give me their personal experiences of Atorvastatin, as I am actually quite worried about what these tablets could do to me.
A: If you have had side effects from one statin, you'll likely have them from another. Do you exercise? Aerobic execise controls my cholesterol pretty well - I don't need medication at this point.
DK
Q: Why is it dangerous for ladies to eat lots of grapefruits/juice whilst on Lipitor® (Atorvastatin)...?
(Please supply references in your responses to bona fide journals/bulletins).
How much is considered "too much?"
Atorvastatin is one of the statin drugs used to treat some forms of hyperlipidaemia. Its MOA is specific inhibition of HMG-CoA reductase.
Thank you.
A: It slows the liver enzymes that metabolize lipitor???? Leads to high concentration of the drug???
I'd say play it safe and abstain from drinking grapefruit juice altogether.
It's too bitter anyways.
Q: When does the Patent expire on Lipitor in Philippines?Is any generic available of Atorvastatin in Philippines ?
A: According to Google it doesn't expire until 2010
Q: Does anyone know the melting point and specific rotation of atorvastatin/lipitor?
A: 176°C to 178°C Atorva Ca
it all depends on which polymorph / Salt u r asking for
Q: does atorvastatin has an adverse effect on erection of penis?
A: It can, anything can cause problems for some people.
In most cases it may help. Clearing cholesterol can improve circulation, You need good circulation for a good erection.
Q: Why LIPITOR (atorvastatin) should not be taken with grape fruit juice?
NB: Grape fruit contains potassium !
NB: I don't mean the cytochrome P450 oxidizing system inhibition, it's for sure related to the potassium but why i don't know!
A: Hi, grapefruit juice turns off an enzyme detoxification system in the liver. The liver is responsible for clearing out toxins and strange things from the blood. If this detoxification system is turned off, the drug is not cleared as quickly from the blood and stays around much longer. This means you'll have a larger dose of the medication than usual.
Hope this helps!
Q: What is the combined effect of atorvastatin and fenofibrate on TG and LDL cholestorol.Is it required take abov
What is the combined effect of atorvastatin and fenofibrate on TG and LDL cholestorol.Is it required take above medicine alongwith GISSICOR ( Composition EPA Eicosapentaenoic acid 280mg & DHA Docosahexaenoic acid 230 mg).
A: atorvastatin is an antilipidemic -which means it controls the amount of fat and cholesterol that circulates in your blood system, not sure about the rest of the question, but if you have a history of stroke, heart attack, or currently have high cholesterol or blood pressure, it is good to be taking it
Q: which are the basic raw materials for manufacturing of atorvastatin?
A: Atorvastatin is completely synthetic:
R-(R*, R*)]-2-(4-fluorophenyl)-beta, delta-dihydroxy-5- (1-methylethyl)-3-phenyl-4- [(phenylamino)carbonyl]-1H- pyrrole-1-heptanoic acid
The chemicals of that compound are then packaged in white powder calcium.
Q: i have been prescribed a ATORVASTATIN. Can i have this during the day or only before bedtime?
A: ATORVASTATIN:HOW TO USE
Take this medication by mouth usually once daily with or without food, or as directed by your doctor. This drug is best taken in the evening.PLEASE REFER TO THIS WEBSITE FOR ALL INFO FOR THIS MEDICATION http://www.webmd.com/drugs/drug-841-Atorvastatin+Oral.aspx?drugid=841&drugname=Atorvastatin+Oral
Q: atorvastatin gives hazy solution with methanol , what is possible reason for that?
A: you need to clean the beaker first
Q: Why two different directions for atorvastatin calcium.One says no grapefruit, the other no alcohol?
A: Probably because both of those things can cause violent side affects when mixed with that medication. Ask your pharmacist to be sure.
Q: for how long one can take aspirin & atorvastatin for cholestrol
A: Aspirin is not used for cholesterol. Its used for thinning the blood I think, you should ask whoever prescribed the atorvastatin.
Q: which are the raw material require for manufacturing of atorvastatin?
A: [R-(R*, R*)]-2-(4-fluorophenyl)-beta, delta-dihydroxy-5- (1-methylethyl)-3-phenyl-4- [(phenylamino)carbonyl]-1H- pyrrole-1-heptanoic acid
Q: Anyone taking the Atorvastatin Calcium (generic Lipitor) manufactured by (I believe) Cipla out of India?
A: Yes. And have no problems with it.
Good luck!